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Search term: STARLIX

STARLIX (nateglinide)
STARLIX 60mg, tablet
STARLIX 120mg, tablet
STARLIX 180mg, tablet

NATEGLINIDE - ORAL

COMMON BRAND NAME(S): Starlix
USES: Nateglinide is used alone or with other medications to control high blood sugar along with a proper diet and exercise program. It is used in people with type 2 (non-insulin-dependent) diabetes. Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, circulation problems, and decreased sexual ability. It works by stimulating the body to produce more insulin. Insulin is a natural substance that allows the body to properly use sugar from the diet.

HOW TO USE: Take this medication by mouth before each meal, usually 2-4 times daily 1-30 minutes before meals or as directed by your doctor. Take this drug no earlier than 30 minutes before the meal. You may also take it just before the meal if necessary. If you are having liquid meals, a higher dose of this medication may be necessary to control your blood sugar. Consult your doctor for more details. The dosage is based on your medical condition, number of meals per day, and response to therapy. Use this medication regularly as directed by your doctor in order to get the most benefit from it. Carefully follow the medication treatment plan, meal plan, and exercise program your doctor has recommended. Monitor your blood sugar on a regular basis. Keep track of the results, and share them with your doctor. This is very important in order to determine the correct nateglinide dose. Inform your doctor if your blood sugar measurements are too high or too low. Your dosage may need to be changed.

SIDE EFFECTS: Nausea, vomiting, diarrhea, upset stomach, joint pain, and flu-like symptoms may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Too much of this medication can cause low blood sugar (hypoglycemia). This effect may also occur if you do not consume enough calories. The symptoms include chills, cold sweats, blurred vision, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands/feet, or hunger. It is a good habit to carry glucose (sugar) tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, raise your blood sugar quickly by eating a quick source of sugar such as table sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Tell your doctor immediately about the reaction. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. Too little of this medication can cause high blood sugar (hyperglycemia). Symptoms of high blood sugar include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, tell your doctor immediately. Your medication dosage may need to be increased. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking nateglinide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: type 1 diabetes (insulin dependent), a certain blood acid complication of uncontrolled diabetes (ketoacidosis). Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal or pituitary gland problems, thyroid problems, severe kidney disease, long-term liver disease, gout, high blood uric acid levels, nerve problems (e.g., diabetic neuropathy), infections, inability to eat due to loss of appetite, nausea/vomiting. Do not change the dose of this medication unless your doctor has given you instructions on how to do so. Follow your doctor's instructions carefully. Know the symptoms of low blood sugar and high blood sugar (see Side Effects section). Tell your doctor immediately if you experience symptoms of high or low blood sugar. Do not use this medication when you have low blood sugar. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar. During times of stress, such as fever, infection, injury, surgery, or quitting smoking, it may be more difficult to control your blood sugar. Consult your doctor because a change in your dose may be required. Changes in your lifestyle or activity level may affect the amount of nateglinide your body needs to control blood sugar levels. If you notice an unusual change in your blood sugar measurements, tell your doctor. Check your blood sugar before and after exercise. You may need a snack before exercising. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first. This drug should not be used with the following medication because very serious interactions may occur: gatifloxacin. If you are currently using the medication listed above, tell your doctor or pharmacist before starting nateglinide. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: warfarin, tolbutamide, phenytoin. Some drugs may affect your blood sugar levels and make control of your blood sugar more difficult. If you start or stop these medications while taking nateglinide, you should check your blood sugar levels more frequently. Tell your doctor or pharmacist if you are taking any of these medications/herbal products: certain "water pills" (e.g., furosemide, hydrochlorothiazide), oral corticosteroids (e.g., prednisone, dexamethasone, prednisolone), phenothiazines (e.g., chlorpromazine, trifluoperazine), newer drugs for mental/mood problems (e.g., olanzapine, clozapine, risperidone, ziprasidone), birth control pills, estrogens, niacin, sympathomimetics (e.g., pseudoephedrine), isoniazid, thyroid drugs, some calcium channel blockers (e.g., nifedipine), some beta blockers (e.g., propranolol), fenugreek, ginseng, gymnema, alcohol, quinolone antibiotics (e.g., ciprofloxacin, levofloxacin), some protease inhibitors (e.g., indinavir, amprenavir), somatropin. Check the labels on all your nonprescription medicines (e.g., cough-and-cold products) because they may contain ingredients that could affect your blood sugar. Ask your pharmacist about the safe use of those products. Other medications can affect the results of urine tests for sugar or ketones. Consult your doctor or pharmacist for more information.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

OVERDOSE: If overdose is suspected, contact your poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: very fast heartbeat, vision changes, unexplained heavy sweating, agitation, fainting, seizures.

MISSED DOSE: If you miss a dose, skip that dose and resume your regular dosage schedule with your next meal. Do not double the dose to catch up.

STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage at 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

NOTES: Do not share this medication with others. It is recommended you attend a diabetes education program to understand diabetes and all the important aspects of its treatment, including meals/diet, exercise, personal hygiene, medications, and getting regular eye, foot, and medical exams. Keep all medical appointments. Laboratory and/or medical tests (e.g., liver and kidney function tests, fasting blood glucose, hemoglobin A1C, complete blood counts) will be performed to monitor for side effects and response to therapy. Wear or carry identification stating that you have diabetes and are using this drug.
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